DMSO, Sterile Filtered A versatile highly polar organic solvent

DMSO, Sterile Filtered (CAS 67-68-5)

DMSO, Sterile Filtered | CAS 67-68-5 is rated 5.0 out of 5 by 1.
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Synonym: Dimethyl sulfoxide
Application: A versatile highly polar organic solvent
CAS Number: 67-68-5
Purity: ≥99%
Molecular Weight: 78.13
Molecular Formula: C2H6OS
* Refer to Certificate of Analysis for lot specific data (including water content).
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DMSO, Sterile Filtered, is a highly polar organic solvent with many applications in chemical and biological research. DMSO can uniquely provide solubility to certain very polar small molecules, such as simple biomolecules with multiple protic functional groups. It can also be used as an oxidation reagent in certain transformations. The yield of PCR processes is amplified with DMSO as a co-solvent, helping to inhibit the formation of secondary structures from DNA fragments. In addition, the solvent has reported uses in the prevention of ice crystal formation during cryopreservation. Ice crystal formation damages cells and tissues and normally results in their death. DMSO is an excellent option for cryopreservation because it is able to penetrate cells and tissues easily, preventing ice formation within the cell and it has low toxicity.
Also available: Dimethyl Sulfoxide (DMSO), cell culture reagent (sc-358801) and as a standard solvent (sc-202581)

Physical State :
Liquid
Solubility :
Soluble in water, ethanol, ether, benzene, chloroform, and acetone.
Storage :
Desiccate at room temperature
Melting Point :
16-19° C (lit.)
Boiling Point :
189° C (lit.)
Density :
1.10 g/mL
Refractive Index :
n20D 1.48 (lit.)
IC50 :
Cytotoxicity against mouse HII4E cells : IC50 = 199 µg/ml
Ki Data :
Choline acetylase: Ki= 25 mM (rat)
pK Values :
pKa: -4.54 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
RTECS :
PV6210000
PubChem CID :
679
Merck Index :
14: 3259
MDL Number :
MFCD00002089
EC Number :
200-664-3
Beilstein Registry :
506008
SMILES :
CS(=O)C

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DMSO, Sterile Filtered  Product Citations

See how others have used DMSO, Sterile Filtered. Click on the entry to view the PubMed entry .

Citations 1 to 5 of 5 total

PMID: # 26386269  Kang, W. et al. 2016. Journal of biomedical materials research. Part A. 104: 283-90.

PMID: # 27179306  Li, X. et al. 2016. Int. Immunopharmacol. 36: 263-70.

PMID: # 26593928  Lee, D. et al. 2015. Int J Environ Res Public Health. 12: 14610-25.

PMID: # 24954315  Baek, SJ. et al. 2014. Yonsei Med. J. 55: 886-94.

PMID: # 23497063  Stewart, P. et al. 2013. BMC Complement Altern Med. 13: 60.

Citations 1 to 5 of 5 total
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Rated 5 out of 5 by from Various publications cite the use of DMSO Various publications cite the use of DMSO to provide solubility to certain very polar small molecules, such as simple biomolecules with multiple protic functional groups. It can also be used as an oxidation reagent in certain transformations. The yield of PCR processes is amplified with DMSO as a co-solvent, helping to inhibit the formation of secondary structures from DNA fragments. -SCBT Publication Review
Date published: 2015-01-23
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