Digitoxigenin A cardenolide that is the aglycon of digitoxin

Digitoxigenin (CAS 143-62-4)

Digitoxigenin | CAS 143-62-4 is rated 5.0 out of 5 by 1.
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Application: A cardenolide that is the aglycon of digitoxin
CAS Number: 143-62-4
Purity: ≥97%
Molecular Weight: 374.51
Molecular Formula: C23H34O4
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Digitoxigenin a cardenolide that is the aglycon of digitoxin.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (partly), alcohol, chloroform, acetone, and ethanol (50 mg/ml).
Storage :
Store at room temperature
Melting Point :
253° C (lit.)
Refractive Index :
n20D 1.59 (Predicted)
Optical Activity :
α20/D +17.5°±2.5°, c = 1 in methanol
IC50 :
Sodium/potassium-transporting ATPase: IC50 = 8 nM (human); TK-10: IC50 = 76.5 nM (human); Na+/K+-ATPase α2: IC50 = 80 nM (human); MCF7: IC50 = 194.4 nM (human); TK-10: IC50 = 317.5 nM (human)
Ki Data :
Monoclonal antibody : Ki= 880 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
FH4975000
Transport :
UN 3462, Class 6.1, Packing group II
PubChem CID :
4369270
Merck Index :
14: 3162
MDL Number :
MFCD00003687
EC Number :
205-603-4
Beilstein Registry :
95448
SMILES :
C[C@]12CC[C@@H](C[C@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@@]3(CC[C@@H]4C5=CC(=O)OC5)O)C)O

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Schneider et al Schneider et al. (PubMed ID 26252521) found that Digitoxigenin inhibited growth and proliferation in human tumor cell lines via down regulation of MMP-2, MMP-9 and p-FAK. -SCBT Publication Review
Date published: 2015-02-17
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