Deoxycholic acid sodium salt An ionic detergent for the solubilization of membrane-bound proteins

Deoxycholic acid sodium salt (CAS 302-95-4)

Synonym: Sodium deoxycholate
Application: An ionic detergent for the solubilization of membrane-bound proteins
CAS Number: 302-95-4
Molecular Weight: 414.55
Molecular Formula: C24H39O4•Na
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Deoxycholic Acid, Sodium Salt is an ionic detergent for the solubilization of membrane-bound proteins. Deoxycholic Acid, Sodium Salt is reported to induce tyrosine phosphorylation of b-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 μM).


References

1. Pai, Rama., et al., 2004. Deoxycholic acid activates beta-catenin signaling pathway and increases colon cell cancer growth and invasiveness. Molecular biology of the cell. 15(5): 2156-63. PMID: 15004225

Physical State :
Solid
Solubility :
Soluble in water (330 g/l) at 15 °C, DMSO, methanol, and ethanol (very slightly).
Storage :
Store at room temperature
Melting Point :
357-365° C
Optical Activity :
α20/D +55°, c = 1 in ethanol; α20/D +45.1°, c = 0.98 in methanol; α20/D 44°, c = 2 in water
pK Values :
pKa: 6.58, 6.2, 4.76 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
FZ2250000
PubChem CID :
23668196
Merck Index :
14: 2899
MDL Number :
MFCD00064139
EC Number :
206-132-7
Beilstein Registry :
3581950
SMILES :
C[C@H](CCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

-->
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 55ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Various publications cite the use of Sodium Various publications cite the use of Sodium deoxycholate (Deoxycholic acid sodium salt), an ionic detergent, for the solubilization of membrane-bound proteins. -SCBT Publication Review
Date published: 2015-06-06
  • y_2018, m_11, d_14, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.8
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_280670, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 256ms
  • REVIEWS, PRODUCT
--%>

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2018 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.