Deoxycholic acid sodium salt An ionic detergent for the solubilization of membrane-bound proteins

Deoxycholic acid sodium salt (CAS 302-95-4)

Synonym: Sodium deoxycholate
Application: An ionic detergent for the solubilization of membrane-bound proteins
CAS Number: 302-95-4
Molecular Weight: 414.55
Molecular Formula: C24H39O4•Na
* Refer to Certificate of Analysis for lot specific data (including water content).
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Deoxycholic Acid, Sodium Salt is an ionic detergent for the solubilization of membrane-bound proteins. Deoxycholic Acid, Sodium Salt is reported to induce tyrosine phosphorylation of b-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 μM).


1. Pai, Rama., et al., 2004. Deoxycholic acid activates beta-catenin signaling pathway and increases colon cell cancer growth and invasiveness. Molecular biology of the cell. 15(5): 2156-63. PMID: 15004225

Physical State :
Solubility :
Soluble in water (330 g/l) at 15 °C, DMSO, methanol, and ethanol (very slightly).
Storage :
Store at room temperature
Melting Point :
357-365° C
Optical Activity :
α20/D +55°, c = 1 in ethanol; α20/D +45.1°, c = 0.98 in methanol; α20/D 44°, c = 2 in water
pK Values :
pKa: 6.58, 6.2, 4.76 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 2899
MDL Number :
EC Number :
Beilstein Registry :

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Rated 5 out of 5 by from Various publications cite the use of Sodium Various publications cite the use of Sodium deoxycholate (Deoxycholic acid sodium salt), an ionic detergent, for the solubilization of membrane-bound proteins. -SCBT Publication Review
Date published: 2015-06-06
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