Decylubiquinone inhibits the Ca2+-dependent mitochondrial permeability transition pore (MPTP), with a maximum effect on Ca2+ retention capacity of rat liver mitochondria at 100 μM. It does not, however, inhibit respiration. Decylubiquinone also inhibits etoposide-induced apoptosis in L929 cells at 5 μM.
Soluble in DMSO (10 mg/ml), chloroform (50 mg/ml), and TRIS buffer.
Store at -20° C
160.22 °C (Predicted)
452.87 °C at 760 mmHg (Predicted)
1.03 g/mL (Predicted)
n20D 1.49 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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PinhoPinho, et al. (PubMed ID 23758163) found that decylubiquinone delayed rotenone, but not myxothiazol-antimycin caused cardiac dysfunction in zebrafish. -SCBT Publication Review
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