DAR-4MA rhodamine-based photo-stable NO fluorescent indicator

DAR-4M

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Synonym: Diaminorhodamine-4M; 3′,6′-Bis(dimethylamino)-9-[3-amino-4-(N-methylamino)-2-carboxyphenyl]xanthylium inner salt
Application: A rhodamine-based photo-stable NO fluorescent indicator
Molecular Weight: 430.50
Molecular Formula: C25H26N4O3
* Refer to Certificate of Analysis for lot specific data (including water content).
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DAR-4M is a rhodamine-based photo-stable nitric oxide (NO) fluorescent indicator with a detection limit of ~10 nM. Reacts with NO, in the presence of oxygen, resulting in a triazolo-rhodamine analog (DAR-4M T) that exhibits about 840-fold greater fluorescence quantum efficiency. DAR-4M's fluorescence intensity is not dependent on pH, unlike DAF-2.


References

1. Kojima, H., et al., 2001. Bioimaging of nitric oxide with fluorescent indicators based on the rhodamine chromophore. Analytical chemistry. 73(9): 1967-73. PMID: 11354477

Formulation :
5mM in DMSO
Physical State :
Liquid
Storage :
Store at -20° C
Melting Point :
18.45° C
Density :
1.1 g/cm3 at 20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
9980126
SMILES :
CN=C1C=CC(=C2C3=C(C=C(C=C3)N(C)C)OC4=C2C=CC(=C4)N(C)C)C(=C1N)C(=O)O

Download SDS (MSDS)

Certificate of Analysis

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