Daptomycin is a lipopeptide antibiotic produced by Streptomyces roseosporus with reported in vitro bactericidal activity against gram-positive organisms. As a calcium-dependent antibiotic, Daptomycin has been reported to act on the cytoplasmic membrane and undergo a conformational change upon interaction with lipid membranes in a model system. After the conformational change occurs, the compound is inserted into the membrane and causes significant perturbations. Membrane depolarization and leakage occurs, causing death in susceptible organisms.
Thank you for your question. Daptomycin, sc-202125, is in off-white to light yellow powder form.
Answered by: Chemical Support 4
Date published: 2017-04-28
Is this product USP grade?
Asked by: Io5ay
Thank you for your question.
This chemical hasn't been manufacturer for USP compliance, however, you can inquire as to the purity of our current lot.
Please contact Technical Service if you have further questions concerning this product.
Rated 5 out of
HuangHuang, XL. et al. (PubMed 25151744) reported that long-circulating liposomal Daptomycin enhances protection against systemic methicillin-resistant Staphylococcus aureus infection in mice. -SCBT Publication Review
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