D-Pantothenic acid is the dextrorotatory (D) isomer of pantothenic acid, and the only isomer to possesses biologic activity. The levorotatory (L) form may antagonize the effects of the dextrorotatory isomer. Pantothenic acid, also called vitamin B5 (a B vitamin), is a water-soluble vitamin and an essential nutrient. Animals require pantothenic acid to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats. D-Pantothenic acid sodium salt is used in research as a synthetic source of Pantothenic acid to study cellular metabolism and CoA activity.
1. Kawai, F. et al. 1979. Meth. Enzymol. 62 : 220 7. PMID: 108510
2. Lin, Y. et al. 2004. Neuroreport. 15(14): 2241-2244. PMID: 15371742
3. Shibata, K. et al. 2013. J. Nutr. Sci. Vitaminol. 59(2): 93-99. PMID: 23727638
Soluble in water (50 mg/ml).
Desiccate at 4° C
n20D ~1.51 (Predicted)
α20/D +28.2°; α20/D +26.75°±1.75°, c = 5 in water
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Various publications cite the use of DVarious publications cite the use of D-Pantothenic acid in studies of vitamin B5 deficiency. -SCBT Publication Review
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