Cytokeratin 3/2p Antibody (AE5)recommended for detection of Cytokeratin 3 of corneal epithelium and Cytokeratin 2p of palate epithelium of mouse, rat, human, rabbit and bovine origin by WB, IP, IF and IHC(P)
Cytokeratin 3/2p Antibody (AE5) is a mouse monoclonal IgG1 (kappa light chain) provided at 200 µg/ml
raised against corneal epithelial Cytokeratin of rabbit origin
recommended for detection of Cytokeratin 3 of corneal epithelium and Cytokeratin 2p of palate epithelium of mouse, rat, human, rabbit and bovine origin by WB, IP, IF and IHC(P); useful as a marker to study corneal epithelial differentiation
available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Cytokeratin 3/2p (AE5): sc-80000.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. The Cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. There are two types of Cytokeratins: types I and II. Type I Cytokeratins are acidic proteins, whereas type II Cytokeratins are neutral or basic proteins. Cytokeratin 3 is a type II Cytokeratin expressed in the corneal epithelium along with Cytokeratin 12. Dominant-negative mutations in the Cytokeratin 3 and Cytokeratin 12 genes cause Meesmann corneal dystrophy (MCD), an autosomal dominant disease that is characterized by weakness of the anterior corneal epithelium. Cytokeratin 2p (also designated Keratin 76) is a type II Cytokeratin expressed in palate epithelium. Cytokeratin 2p and Cytokeratin 3 proteins share significant sequence identity at the amino acid level.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences