Cyclosporine An immunopsupressent thought to bind to cyclophilin in T-lymphocytes

Cyclosporine (CAS 79217-60-0)

Cyclosporine | CAS 79217-60-0 is rated 5.0 out of 5 by 1.
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Application: An immunopsupressent thought to bind to cyclophilin in T-lymphocytes
CAS Number: 79217-60-0
Purity: ≥99%
Molecular Weight: 1202.61
Molecular Formula: C62H111N11O12
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits
Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (Slightly), saturated hydrocarbons (Slightly), methanol, acetone, diethyl ether, chloroform, DMSO (148 mg/mL ) at 25 °C, and ethanol (241 mg/mL ) at 25 °C.
Storage :
Store at -20° C
Melting Point :
148-151° C
Density :
1.02 g/cm3
Refractive Index :
n20D 1.47
Optical Activity :
α20/D -244°, c = 0.6 in chloroform; α20/D - 189°, c = 0.5 in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
6435893
MDL Number :
MFCD01771104
SMILES :
CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C

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Certificate of Analysis

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Cyclosporine  Product Citations

See how others have used Cyclosporine. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 24675888  Feine, O. et al. 2014. Cell Cycle. 13: 1727-36.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Miyata et al Miyata et al. (PubMed ID 26429887) found that that the cacineurin inhibitor, Cyclosporine, reversibly prevented mouse fertility via PPP3CC/PPP3R2 interaction. -SCBT Publication Review
Date published: 2015-06-26
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