Cyanogen bromideA protein cleaving agent for immobilization procedures

Cyanogen bromide (CAS 506-68-3)

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Synonym: Bromine cyanide
Application: A protein cleaving agent for immobilization procedures
CAS Number: 506-68-3
Molecular Weight: 105.92
Molecular Formula: BrCN
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Cyanogen bromide has been used in protein immobilization procedures, and to cleave peptides to find the low resolution structure of a protein. This product is also used dissolved in acetonitrile (sc-207252) to activate agarose (sc-280594) for affinity chromatography.


References

1. Sugiyama, Y., et al. 2008. Anal. Biochem. 373: 173-175. PMID: 17963683
2. Shi, T., et al. 2009. Anal. Chem. 81: 9885-9895. PMID: 19924875
3. Andreev, Y.A., et al. 2010. Anal. Biochem. 407: 144-146. PMID: 20670609

Appearance :
crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (slightly with decomposition and release of toxic gases), chloroform, dichloromethane, ethanol (readily), and acetonitrile.
Storage :
Store at 4° C
Melting Point :
50-53° C (lit.)
Boiling Point :
61-62° C (lit.)
Density :
2.02 g/cm3 at 20° C
Refractive Index :
n20D 1.47 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
GT2100000
Transport :
Only available in the continental United States. Not available for air transport.
PubChem CID :
10476
Merck Index :
14: 2693
MDL Number :
MFCD00011597
EC Number :
208-051-2
Beilstein Registry :
1697296
SMILES :
C(#N)Br

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Certificate of Analysis

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