Crotamiton An antipruritic with antibacterial properties

Crotamiton (CAS 483-63-6)

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Synonym: Crotamitex; Eurax; Euraxil; Veteusan; N-Ethyl-N-(2-methylphenyl)-2-butenamide
Application: An antipruritic with antibacterial properties
CAS Number: 483-63-6
Purity: ≥98%
Molecular Weight: 203.28
Molecular Formula: C13H17NO
* Refer to Certificate of Analysis for lot specific data (including water content).
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Crotamiton is an acaricide and that has action against scabies. The compound has been shown to be effective against pruritus of breast carcinoma skin infiltration. Crotamiton also retains marked antibacterial properties.


References

1. Konstantinov, D., et al. 1979. J. Int. Med. Res. 7: 443-448. PMID: 499647
2. Holme, S.A., et al. 2001. J Pain Symptom Manage. 22: 803-805. PMID: 11596612
3. Buffet, M. and Dupin, N. 2003. Fundam Clin Pharmacol. 17: 217-225. PMID: 12667233

Physical State :
Liquid
Solubility :
Soluble in water (1:500), alcohol, methanol, ether, and ethanol.
Storage :
Store at room temperature
Melting Point :
<25° C
Boiling Point :
153-155° C (lit.) at 13 mmHg
Density :
0.99 g/mL at 25° C
Refractive Index :
n20D 1.55
pK Values :
pKb: 1.14 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
GQ7000000
PubChem CID :
688020
Merck Index :
14: 2594
MDL Number :
MFCD00026989
EC Number :
207-596-3
Beilstein Registry :
3275497
SMILES :
CCN(C1=CC=CC=C1C)C(=O)C=CC

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Certificate of Analysis

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Crotamiton  Product Citations

See how others have used Crotamiton. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 26253722  Kataria, H. et al. 2015. Mol. Neurobiol.

Citations 1 to 1 of 1 total
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