Creatine zinc chloride is the end product of creatine catabolism. Normal constituent of urine; daily output about 25 mg/kg body weight. Increased amounts in the urine are typically associated with substantially impaired renal function. Also found together with creatine in muscle tissues and blood. Reacts with picric acid under alkaline conditions to form a Janovski complex. The rate of formation of the colored complex, measured at 480-520 nm is proportional to the creatinine concentration.
1. Merck Index, 12th Ed., No. 2638. 2. Butler, A.R. and Glidewell, C., "Creatinine: an examination of its structure and some of its reactions by synergistic use of MNDO calculations and nuclear magnetic resonance spectroscopy." J. Chem. Soc. Perkin Trans., v. 2, 1465-1468 (1985). 3. Hirate, et al., "The effect of sacrificing method on the tissue concentration of exogeneous creatinine in rats." Chem. Pharm. Bull., v. 33(11), 5105-5107 (1985). 4. Kim, et al., "Sarcosine oxidase involved in creatinine degradation in Alcaligenes denitrificans subsp. denitrificans J9 and Arthrobacter spp. J5 and J11." Agric. Biol. Chem., v. 50(11), 2811-2816 (1986). 5. Nakamura, et al., "Creatones A and B. Revision of the structure for the product of oxidation of creatinine and creatine." Bull. Chem. Soc. Jpn., v. 63(5), 1540-1542 (1990). 6. Valcour, A.A. and Woodworth, R.C., J. Magn. Reson., v. 66, 536 (1986). 7. Welch, M.J., et al., "Determination of serum creatinine by isotope dilution mass spectrometry as a candidate definitive method." Anal. Chem., v. 58(8), 1681-1685 (1986) 8. Winquist, et al., "Determination of creatinine by an ammonia-sensitive semiconductor structure and immobilized enzymes." Anal. Chem., v. 58(1), 145-148 (1986). 9. Yokozawa, et al., "Changes in the urinary constituents in rats with chronic renal failure during oral administration of rhubarb extract." Chem. Pharm. Bull., v. 33(10), 4508-4514 (1985).
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2017 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.