CPSF6 Antibody (F-3) is a mouse monoclonal IgG1 (kappa light chain) provided at 200 µg/ml
raised against amino acids 167-225 mapping within an internal region of CPSF6 of human origin
recommended for detection of CPSF6 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine and bovine
available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of CPSF6 (F-3): sc-376228.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
3′ ends of eukaryotic mRNAs can undergo processing events that include endonucleolytic cleavage and polyadenylation. Cleavage and polyadenylation specificity factors (CPSF) mediate 3′ cleavage of the transcript and subsequent polyadenylation. CPSF6, also known as CFIm68 (mammalian cleavage factor I, 68 kDa subunit), HPBRII-4 or HPBRII-7, is a member of the CPSF6/7 family and contains an N-terminal RNA recognition motif (RRM) and a C-terminal RS-like domain. Via its RS-like domain, CPSF6 interacts with SRp20, Tra-2β and 9G8. CPSF6 localizes to the paraspeckles and forms a heterodimer with NUDT21, comprising the CFIm complex which is essential for the first step in pre-mRNA 3′ cleavage and polyadenylation processing. CPSF6 is the larger subunit of the complex and is present in only half of the two heterodimer combinations (the other half being a dimer of NUDT21 and CPSF7).
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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