Corticosterone is a hormone synthesized in response to stress. It binds and activates MCRs(mineralocorticoid receptors) and GRs (glucocorticoid receptors), which results in altered expression. This eventually affects ionic conductances through the membrane. Corticosterone induces apoptosis in murine bone marrow.
1. de Kloet, E.R. 1992. Ann. N. Y. Acad. Sci. 663: 357-371. PMID: 1336332 2. Joëls, M., et al. 1992. Trends Neurosci. 15: 25-30. PMID: 1374954 3. Garvy, B.A., et al. 1993. Immunology. 80: 587-592. PMID: 8307608
Soluble in acetone, methanol, ethanol (10 mM), chloroform, and DMSO (100 mM). Insoluble in water.
Store at room temperature
179-183° C (lit.)
~529.25° C at 760 mmHg (Predicted)
~1.22 g/cm3 (Predicted)
n20D 1.58 (Predicted)
α20/D +223°±3°, c = 1 in ethanol
Sigma opioid receptor: Ki= 35.6 µM (human)
pKa: 12.98 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Taves et alTaves et al. (PubMed ID 26366679) found that Corticosterone produced by avian adrenals was necessary for adequate lymphocyte development in zebra finches. -SCBT Publication Review
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