Colistin sulfate, a cationic polypeptide from the polymyxin family, has been shown to be an extremely potent antibiotic that is effective against most gram-negative Bacilli. Mechanistic studies have reported that this compound induces apoptosis through interaction with the cytoplasmic membrane. Additional studies have demonstrated that Colistin sulphate is extremely toxic. Toxic effects noted include neurotoxicity, nephrotoxicity, vascular congestion of brain vessels, and extreme kidney and CNS negative effects.
1. David, H.L., et al. 1985. Antimicrob. Agents Chemother. 27: 701-707. PMID: 4015067 2. Evans, M.E., et al. 1999. Ann Pharmacother. 33: 960-967. PMID: 10492501 3. Landman, W.J., et al. 2000. Avian Pathol. 29: 593-601. PMID: 19184856 4. Beringer, P. 2001. Curr Opin Pulm Med. 7: 434-440. PMID: 11706322
Soluble in water (50mg/ml)
Store at -20° C
α20/D -65°, c = 1 in water
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.