Binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity. Antimicrobial spectrum: Gram-negative bacteria. Cyclopolypeptide antibiotic. Endotoxin-binding capacity.
1. M.J. Rogers, J. Cohen Infection (Munich) 14, 79, (1986)
Soluble in water (10 mg/ml).
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Gregoire et alGregoire et al. (PubMed ID 25267662) found that Colistin sodium methanesulfonate renal clearance and colistin concentrations at steady state are mostly governed by creatinine clearance. -SCBT Publication Review
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