Cochliodinol An antibiotic metabolite of Chaetomium cochliodes and C. globosum

Cochliodinol (CAS 11051-88-0)

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Application: An antibiotic metabolite of Chaetomium cochliodes and C. globosum
CAS Number: 11051-88-0
Purity: ≥97%
Molecular Weight: 506.6
Molecular Formula: C32H30N2O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Cochliodinol is an antibiotic metabolite of Chaetomium cochliodes and C. globosum. Shown to inhibit the metabolism and growth of a variety of bacterial genera. Also shown to inhibit some species from many genera of microfungi. Cochliodinol is the first reported asterriquinone structure isolated from Chaetomium species. Asterriquinone is an antitumor metabolite, and thus cochliodinol has been reported to exhibit antitumor activity.


References

1. Brewer, D., et al. 1970. Can. J. Microbiol. 16: 433-440. PMID: 4987295
2. Brewer, D., et al. 1984. Can. J. Microbiol. 30: 1068-1072. PMID: 6541963
3. Mocek, U., et al. 1996. J. Antibiot. 49: 854-859. PMID: 8931717
4. Kaji, A., et al. 1997. Anticancer Res. 17: 3675-3679. PMID: 9413222

Physical State :
Solid
Derived From :
Chaetomium globosum
Solubility :
Soluble in DMSO, and 100% ethanol.
Storage :
Store at -20° C
Boiling Point :
789.96° C at 760 mmHg (Predicted)
Density :
~1.3 g/cm3 (Predicted)
Refractive Index :
n20D 1.73 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
DK3529000
PubChem CID :
2827
MDL Number :
MFCD01663132
Beilstein Registry :
5188623
SMILES :
CC(=CCC1=CC2=C(C=C1)NC=C2C3=C(C(=O)C(=C(C3=O)O)C4=CNC5=C4C=C(C=C5)CC=C(C)C)O)C

Download SDS (MSDS)

Certificate of Analysis

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