Cobalt(II) chloride hexahydrate Cobalt(II) chloride hexahydrate is inducer of HIF-1 production used to study apoptotic effects in HepG2 cells.

Cobalt(II) chloride hexahydrate  (CAS 7791-13-1)

Cobalt(II) chloride hexahydrate is rated 5.0 out of 5 by 1.
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| See 1 Citations
Synonym: Chlorek cobaltawy; Cobalt chloride hexahydrate; Cobaltous chloride, hexahydrate; Cobalt chloride, hexahydrate; cobalt chloride hydrate
Application: An inducer of HIF-1 production used to study apoptotic effects in HepG2 cells
CAS Number: 7791-13-1
Purity: ≥98%
Molecular Weight: 237.93
Molecular Formula: CoCl26H2O
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
Cobalt(II) chloride hexahydrate sc-203004 25 g $25.00
Cobalt(II) chloride hexahydrate sc-203004A 100 g $83.00

Cobalt(II) chloride hexahydrate is the most common form of this inorganic compound which is a deep rose color in the hydrated form. The dramatic color change of blue-purple Cobalt(II) chloride (sc-252623) to the rose color when hydrated makes Cobalt(II) chloride an excellent indicator for water in dessicants. As an inducer of HIF-1 production, Cobalt(II) chloride (CoCl2) has been used to study apoptotic effects in HepG2 cells. Also reported as a stabilizer for reconstitution of the radiopharmaceutical technetium-99m exametazime. CoCl2 has been used in studies to examine heat shock protein expression of inflamed skin.


References

1. Palit, S., et al. 1991. Biol Trace Elem Res. 29: 139-145. PMID: 1713470
2. Piret, J.P., et al. 2002. Ann. N. Y. Acad. Sci. 973: 443-447. PMID: 12485908
3. Nordlind, K. 2002. Immunopharmacol Immunotoxicol. 24: 383-394. PMID: 12375735
4. Gartshore, G., et al. 1994. Eur J Nucl Med. 21: 913-923. PMID: 7995284

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in water (970 g/ml at 20° C), acetone, ether, and alcohols.
Storage :
Store at room temperature
Melting Point :
°C
Density :
1.92 g/cm3 at 20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
GG0200000
Transport :
UN 3077, Class 9, Packing group III
PubChem CID :
24643
Merck Index :
14: 2437
MDL Number :
MFCD00149652
EC Number :
231-589-4
SMILES :
O.O.O.O.O.O.[Cl-].[Cl-].[Co+2]

Download SDS (MSDS)

Certificate of Analysis

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Cobalt(II) chloride hexahydrate Product Citations

See how others have used Cobalt(II) chloride hexahydrate. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 22349827
Yin, G. et al. 2013. Constitutive proteasomal degradation of TWIST-1 in epithelial-ovarian cancer stem cells impacts differentiation and metastatic potential. Oncogene. 32: 39-49.

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Rated 5 out of 5 by from Various publications cite the use of Cobalt(II) Various publications cite the use of Cobalt(II) chloride hexahydrate, an Cobalt(II) chloride hexahydrate, to study apoptotic effects in HepG2 cells. -SCBT Publication Review
Date published: 2015-02-16
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