Closantel Closantel is an antihelmintic agent and a potentially useful compound for studying P-glycoprotein interactions in vitro

Closantel  (CAS 57808-65-8)

Closantel is rated 5.0 out of 5 by 1.
  • 2016-09-30T11:24CST
  • bvseo_cps, prod_bvrr, vn_cps_3.4.0
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202548, PRD, sort_relevancy
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 93ms
  • REVIEWS, PRODUCT
Synonym: N-(5-Chloro-4-[(R,S)-(4-chlorophenyl)cyanomethyl]-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide
Application: Potentially useful for studying P-glycoprotein interactions in vitro
CAS Number: 57808-65-8
Purity: ≥98%
Molecular Weight: 663.07
Molecular Formula: C22H14Cl2I2N2O2
* Refer to Certificate of Analysis for lot specific data (including water content).
submit a review for this product and receive 15 cruzcredits

Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
Closantel sc-202548 50 mg $120.00

Closantel is an antihelmintic agent and a potentially useful compound for studying P-glycoprotein interactions in vitro.

Physical State :
Solid
Solubility :
Insoluble in water.
Storage :
Store at 4° C
Melting Point :
218-223° C
Boiling Point :
~590.5° C at 760 mmHg (Predicted)
Density :
~1.9 g/cm3 (Predicted)
Refractive Index :
n20D 1.74 (Predicted)
IC50 :
TXA synthase: IC50 = 64 nM (human); Adenosine A3-R: IC50 = 96 nM (human); EGFR: IC50 = 564 nM (human); p38α: IC50 = 656 nM (human); Fyn: IC50 = 939 nM (human)
Ki Data :
Adenosine A3-R: Ki= 54 nM (human); Chitinase: Ki= 468 nM (Onchocerca volvulus); α2B-AR: Ki= 821.9 nM (human); α2C-AR: Ki= 1 µM (human); DAT: Ki= 3.8 µM (human)
pK Values :
pKa: 5.99 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
CV2444250
Transport :
UN 2811, Class 6.1, Packing group III
PubChem CID :
42574
Merck Index :
14: 2411
MDL Number :
MFCD00661151
EC Number :
260-967-1
SMILES :
CC1=C(NC(=O)C2=C(O)C(I)=CC(I)=C2)C=C(Cl)C(=C1)C(C#N)C1=CC=C(Cl)C=C1

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

You May Also Like

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 77ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Dravid et al Dravid et al. (PubMed ID 26281757) used the chitinase inhibitor, closantel, to block microfilariae endochitinase in Setaria cervi. -SCBT Publication Review
Date published: 2015-05-03
  • 2016-09-30T11:24CST
  • bvseo_cps, prod_bvrr, vn_cps_3.4.0
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202548, PRD, sort_relevancy
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 5ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2016 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.