Climbazole A potent inducer and inhibitor of P450-dependent metabolizing enzymes

Climbazole (CAS 38083-17-9)

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Application: A potent inducer and inhibitor of P450-dependent metabolizing enzymes
CAS Number: 38083-17-9
Purity: 98%
Molecular Weight: 292.76
Molecular Formula: C15H17ClN2O2
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Climbazole is a potent inducer and inhibitor of P450-dependent drug metabolizing enzymes, which is also used as antifungal and antidandruff agent.


References

Mayser P, Argembeaux H, Rippke F. J Cosmet Sci. 54:263-70 (2003). Kobayashi Y et al. Biol Pharm Bull. 25:53-7 (2002).

Physical State :
Solid
Solubility :
Soluble in water (0.06 mg/ml at 25° C), isopropanol, cyclohexanone, chloroform, and methanol.
Storage :
Store at -20° C
Melting Point :
96.5° C
Boiling Point :
260° C (lit.)
Density :
1.32 g/cm3 at 20° C
Refractive Index :
n20D 1.54
pK Values :
pKb: 5.66 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
EL7085000
PubChem CID :
37907
MDL Number :
MFCD00055505
EC Number :
253-775-4
Beilstein Registry :
618020
SMILES :
CC(C)(C)C(=O)C(N1C=CN=C1)OC2=CC=C(C=C2)Cl

Download SDS (MSDS)

Certificate of Analysis

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POR FAVOR COTIZAR 1 KG DE CLIMBAZOL

Asked by: Gabriela Rossi
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Answered by: Technical Service
Date published: 2017-07-04
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