Ciclopirox Olamine A substituted pyridone antimycotic

Ciclopirox Olamine (CAS 41621-49-2)

Ciclopirox Olamine | CAS 41621-49-2 is rated 5.0 out of 5 by 1.
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Synonym: Ciclopiroxolamine
Application: A substituted pyridone antimycotic
CAS Number: 41621-49-2
Purity: ≥98%
Molecular Weight: 268.35
Molecular Formula: C12H17NO2•C2H7NO
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
Ciclopirox Olamine sc-204688 1 g $47.00
Ciclopirox Olamine sc-204688A 5 g $152.00

Ciclopirox Olamine is a substituted pyridone antimycotic. Has activity against a broad spectrum of dermatophytes, yeasts, actinomycetes, molds, other fungi, and a variety of bacteria.


References

Jue SG, Dawson GW, Brogden RN. Drugs. 29:330-341 (1985).

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in ethanol (30 mg/ml at 25° C), water (<1 mg/ml at 25° C), methanol (50 mg/ml), and DMSO (6 mg/ml at 25° C).
Storage :
Store at room temperature
Melting Point :
143° C
Boiling Point :
350° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.58 (Predicted)
IC50 :
liver stage Plasmodium berghei infection: IC50 = 1.05 µM (Plasmodium berghei); chloroquine-sensitive Plasmodium falciparum NF54: IC50 = 8.2 µM; HepG2: IC50 = >100 µM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
RTECS :
UU7785500
PubChem CID :
38911
Merck Index :
14: 2266
MDL Number :
MFCD00078997
EC Number :
255-464-9
SMILES :
CC1=CC(=O)N(C(=C1)C2CCCCC2)O.C(CO)N

Download SDS (MSDS)

Certificate of Analysis

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What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. This chemical is supplied as a white or light yellow powder. Please contact Technical Service if you have further questions concerning this product.
Answered by: Tech Service 9
Date published: 2017-01-16

What is the solubility of this product?

Asked by: hawkeye11
Thank you for your question. Ciclopirox Olamine, sc-204688, is soluble in DMSO at 6 mg/mL, Water at &lt;1 mg/mL, and Ethanol at 30 mg/mL.
Answered by: TechService7
Date published: 2017-01-20
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Rated 5 out of 5 by from Zhou Zhou, H. et al. (PubMed 25294812) found that Ciclopirox Olamine induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway in Rh30 and RD cells. -SCBT Publication Review
Date published: 2015-04-02
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