Cerulenin (source Cephalosporium caerulens) An inhibitor fatty acid and sterol biosynthesis

Cerulenin (source Cephalosporium caerulens) (CAS 17397-89-6)

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Synonym: Helicocerin; (2R,3S,E,E)-2,3-Epoxy-4-oxo-7,10-dodecadienamide
Application: An inhibitor fatty acid and sterol biosynthesis
CAS Number: 17397-89-6
Purity: ≥98%
Molecular Weight: 223.27
Molecular Formula: C12H17NO3
* Refer to Certificate of Analysis for lot specific data (including water content).
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Cerulenin has broad application in lipid biochemistry as an inhibitor fatty acid and sterol biosynthesis. Cerulenin binds to β-keto-acyl-ACP .synthase blocking the interaction of malonyl CoA. Cerulenin also an inhibits bacterial fatty acid synthesis, acting on the FabH, FabB and FabF condensation enzymes. Cerulenin stimulates fatty acid oxidation and inhibits HMG-CoA synthetase activity.

Appearance :
Powder
Physical State :
Solid
Derived From :
Cephalosporium caerulens
Solubility :
Soluble in acetone (19.60 - 20.40 mg/ml), DMSO (> 10 mg/ml), and 100% ethanol (> 10 mg/ml).
Storage :
Store at -20° C
Melting Point :
93° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
JR1670000
PubChem CID :
5352018
Merck Index :
14: 2004
MDL Number :
MFCD00077686
EC Number :
241-424-8
Beilstein Registry :
4140423
SMILES :
C/C=C/C/C=C/CCC(=O)C1C(O1)C(=O)N(O1)C(=O)N

Download SDS (MSDS)

Certificate of Analysis

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