Ceftriaxone, Disodium Salt, Hemiheptahydrate A potentially useful antibacterial agent for proteomics research

Ceftriaxone, Disodium Salt, Hemiheptahydrate (CAS 104376-79-6)

Ceftriaxone, Disodium Salt, Hemiheptahydrate | CAS 104376-79-6 is rated 5.0 out of 5 by 1.
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Synonym: Ro-13-9904/001; Rocefin; Rocephine
Application: A potentially useful antibacterial agent for proteomics research
CAS Number: 104376-79-6
Purity: ≥92%
Molecular Weight: 661.60
Molecular Formula: C18H16N8Na2O7S33.5H2O
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ceftriaxone, Disodium Salt, Hemiheptahydrate is used as an antibacterial agent. Ceftriaxone is used to study drug-induced immune hemolytic anemias prophylactic strategies to reduce neonatal encephalopathy pentylenetetrazole-evoked convulsions the effect of expression, binding, and inhibition of PDP1 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis. Ceftriaxone is a third-generation cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It is effective against gram-positive and gram-negative bacteria. Ceftriaxone is thought to increase EAAT2 pump expression in the central nervous system and to reduce glutamatergic toxicity.


References

Reiner, R., et al.: J. Antibiot., 33, 783 (1980)

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in Water
Storage :
Store at -20° C
Melting Point :
>190° C (dec.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
11953897
MDL Number :
MFCD01750405
EC Number :
277-930-0
SMILES :
CN1N=C(C(=O)N=C1SCC2=C(N3C(=O)[C@H]([C@H]3SC2)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)C(=O)[O-])[O-].CN1N=C(C(=O)N=C1SCC2=C(N3C(=O)[C@H]([C@H]3SC2)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)C(=O)[O-])[O-].O.O.O.O.O.O.O.[Na+].[Na+].[Na+].[Na+]

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Certificate of Analysis

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Ceftriaxone, Disodium Salt, Hemiheptahydrate  Product Citations

See how others have used Ceftriaxone, Disodium Salt, Hemiheptahydrate. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25964214  Zumkehr, J. et al. 2015. Neurobiology of aging. 36: 2260-71.

Citations 1 to 1 of 1 total

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. The compound, sc-211050, is provided as a white to off-white crystalline powder. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2017-02-14
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Rated 5 out of 5 by from Krezmien et al Krezmien et al. (PubMed ID 26384120) treated a patient with acute pyelonephritis using the antibacterial, Ceftriaxone, Disodium Salt, Hemiheptahydrate, and found the drug caused gall bladder enlargement. -SCBT Publication Review
Date published: 2015-02-05
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