Ceftriaxone, Disodium Salt, Hemiheptahydrate is used as an antibacterial agent. Ceftriaxone is used to study drug-induced immune hemolytic anemias prophylactic strategies to reduce neonatal encephalopathy pentylenetetrazole-evoked convulsions the effect of expression, binding, and inhibition of PDP1 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis. Ceftriaxone is a third-generation cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It is effective against gram-positive and gram-negative bacteria. Ceftriaxone is thought to increase EAAT2 pump expression in the central nervous system and to reduce glutamatergic toxicity.
Reiner, R., et al.: J. Antibiot., 33, 783 (1980)
Soluble in Water
Store at -20° C
>190° C (dec.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Krezmien et alKrezmien et al. (PubMed ID 26384120) treated a patient with acute pyelonephritis using the antibacterial, Ceftriaxone, Disodium Salt, Hemiheptahydrate, and found the drug caused gall bladder enlargement. -SCBT Publication Review
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