Cefotaxime sodium salt A β-lactamase resistant antibiotic

Cefotaxime sodium salt (CAS 64485-93-4)

Cefotaxime sodium salt | CAS 64485-93-4 is rated 5.0 out of 5 by 1.
  • y_2019, m_3, d_25, h_1
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.11
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202989, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 83ms
  • REVIEWS, PRODUCT
Synonym: Cephotaxime; Sym-methoxyimino Cephalosporin; Claforan
Application: A β-lactamase resistant antibiotic
CAS Number: 64485-93-4
Purity: 95%
Molecular Weight: 477.45
Molecular Formula: C16H16N5O7S2•Na
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Cefotaxime Sodium Salt is a third generation Cephalosporin β-lactamase resistant antibiotic with efficacy in prohibition of gram-positive and gram-negative bacterial cell wall synthesis. The compound has demonstrated greater activity than other available first- and second-generation cephalosporins against Enterobacteriaceae. More active than older cephalosporins against Pseudomonas aeruginosa and Acinetobacter spp., but most strains are still considered resistant. Also active against some gram-negative bacilli that are resistant to aminoglycosides, including amikacin (sc-278692). Activity comparable with other cephalosporins against gram-positive cocci, except staphylococci and enterococci, which are resistant. In combination with penicillins or aminoglycosides may be synergistic against selected gram-negative bacilli.


References

1. Dudley, M.N. and Barriere, S.L. 1982. Clin Pharm. 1: 114-124. PMID: 6309465
2. Vallée, F., et al. 1991. Antimicrob. Agents Chemother. 35: 2057-2064. PMID: 1759827
3. Molinari, G., et al. 1991. J Chemother. 3: 6-12. PMID: 2019866

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (>50 mg/ml).
Storage :
Store at -20° C
Melting Point :
163° C
Refractive Index :
n20D 1.78 (Predicted)
Optical Activity :
α20/D +61°±3°, c = 1 in water
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
RTECS :
XI0250000
PubChem CID :
10695961
Merck Index :
14: 1933
MDL Number :
MFCD00079073
EC Number :
264-915-9
Beilstein Registry :
5711411
SMILES :
CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OC)/C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+]

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 78ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Molinari et al Molinari et al. (PubMed ID 2019866) verified cefotaxime s antibiotic activity against Bacteroides strains. -SCBT Publication Review
Date published: 2015-03-07
  • y_2019, m_3, d_25, h_1
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.11
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202989, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 218ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.