Cefonicid sodiumA broadspectrum cephalosporin antibiotic

Cefonicid sodium (CAS 61270-78-8)

Cefonicid sodium | CAS 61270-78-8 is rated 5.0 out of 5 by 1.
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Synonym: Cefonicid disodium salt
Application: A broadspectrum cephalosporin antibiotic
CAS Number: 61270-78-8
Molecular Weight: 586.52
Molecular Formula: C18H16N6O8S32Na
* Refer to Certificate of Analysis for lot specific data (including water content).
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Cefonicid sodium is a broadspectrum cephalosporin antibiotic which inhibits the formation of the bacterial cell wall. Studies suggest that Cefonicid sodium can inhibit the carnitine/carnitine antiport when it is added internally and externally to proteoliposomes. It is known that the molecule contains various electroactive groups that can be detected using adsorptive square-wave stripping voltammetry. In addition, the compound can be detected in solution using UV spectroscopy at 265 nm. Studies indicate that Cefonicid sodium is effective against Escherichia coli, Klebsiella, Citrobacter, Enterobacter, indole-negative Proteus, and Providencia.


References

1. Grappel, S.F., et al. 1980. J. Antibiot. 33: 85-87. PMID: 7372555
2. Dudley, M.N., et al. 1984. Clin Pharm. 3: 23-32. PMID: 6365414
3. Radi, A., et al. 2003. J Pharm Biomed Anal. 31: 1041-1046. PMID: 12667920
4. Pochini, L., et al. 2008. Chem. Biol. Interact. 173: 187-194. PMID: 18452908

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water, DMSO, and methanol.
Storage :
Store at 4° C
Melting Point :
>184° C (dec.)
Refractive Index :
n20D 1.85 (Predicted)
Optical Activity :
α20D -46.3°, c = 0.20 in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
43593
MDL Number :
MFCD00941437
SMILES :
C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)O)C(=O)[O-])CSC4=NN=NN4CS(=O)(=O)[O-].[Na+].[Na+]

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Cefonicid sodium Cefonicid sodium, reported as a cephalosporin antibiotic whose bactericidal mechanism of action is cell wall synthesis inhibition. It is widely used for urinary tract infections, soft tissue and bone infections, and lower respiratory tract infections. -SCBT Publication Review
Date published: 2015-07-08
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