Cdk1/5 Inhibitor is a 3-amino substituted pyrazoloquinoxaline compound that acts as a selective inhibitor of Cdk1 and Cdk5 (IC50 = 600 nM for Cdk1/cyclin B and 400 nM for Cdk5/p25. Cdk1/5 Inhibitor is also shown to inhibit GSK-3β with (IC50 > 10 μM). Cdk1/5 Inhibitor does not inhibit Cdc25 phosphatase activity (IC50 > 10 μM).
1. Ortega, Miguel A., et al., 2002. Pyrazolo[3,4-b]quinoxalines. A new class of cyclin-dependent kinases inhibitors. Bioorganic & medicinal chemistry. 10(7): 2177-84. PMID: 11983514
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.