CD 3254 CD 3254 is a selective RXRα agonist which is reported to not exhibit activity at RARα. RARβ or RARγ receptors.

CD 3254  (CAS 196961-43-0)

CD 3254 is rated 5.0 out of 5 by 1.
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Synonym: 3-[4-Hydroxy-3-(5,6,7,8-tetrahtdro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoic acid
Application: A selective RXRα agonist
CAS Number: 196961-43-0
Purity: ≥97%
Molecular Weight: 364.48
Molecular Formula: C24H28O3
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
CD 3254 sc-358786 10 mg $185.00
CD 3254 sc-358786A 50 mg $793.00

CD 3254 is a selective RXRα agonist which is reported to not exhibit activity at RARα, RARβ or RARγ receptors. RXRα belongs to the NR2B nuclear receptor family and primarily expressed in the liver, intestines, kidneys, and epidermis.


References

1. Pogenberg, V., et al. 2005. J. Biol. Chem. 280: 1625-1633. PMID: 15528208
2. Nahoum, V., et al. 2007. Proc .Natl. Acad. Sci. 104: 17323-17327. PMID: 17947383
3. le Maire, A., et al. 2009. EMBO. Rep. 10: 367-373. PMID: 19270714

Physical State :
Solid
Solubility :
Soluble in ethanol (100 mM), and DMSO (100 mM).
Storage :
Store at -20° C
Refractive Index :
n20D 1.59 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
44566110
SMILES :
CC1=CC2=C(C=C1C3=C(C=CC(=C3)/C=C/C(=O)O)O)C(CCC2(C)C)(C)C

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from le Maire et al le Maire et al. (PubMed ID 19270714) found that the RXR- agonist, CD 3254, potentiated recruitment of the fluorescein-labelled PGC-1 peptide by RXR- and PPAR- . -SCBT Publication Review
Date published: 2015-02-25
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