caspase-8 Inhibitor An inhibitor of caspase-8 and granzyme B

caspase-8 Inhibitor (CAS 191338-86-0)

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Synonym: Granzyme B inhibitor; Ac-IETD-CHO
Application: An inhibitor of caspase-8 and granzyme B
CAS Number: 191338-86-0
Purity: ≥95%
Molecular Weight: 502.52
Molecular Formula: C21H34N4O10
* Refer to Certificate of Analysis for lot specific data (including water content).
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caspase-8 inhibitor is a reversible inhibitor of caspase-6, -8 and granzyme B. It is also known to inhibit caspase-10.

Physical State :
Solid
Sequence :
Ac-Ile-Glu-Thr-Asp-CHO
Storage :
Store at -20° C
Density :
1.3 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
16760475
SMILES :
CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@H](C)O)C(=O)N[C@@H](CC(=O)O)C=O)NC(=O)C

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Certificate of Analysis

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caspase-8 Inhibitor  Product Citations

See how others have used caspase-8 Inhibitor. Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 18231987  2008. J. Cell. Physiol. 216: 153-61.

PMID: # 16615113  2006. Int. J. Cancer. 119: 1236-48.

Citations 1 to 2 of 2 total

hey..in aim to reconstitute how much volume of distilled water need? ist cooled or room temperature distilled water? and after reconstitute what the best temprature to store this solution in order to use after 1 week? thanks again

Asked by: azoz
Thank you for your question. Regarding our research chemical product, caspase-8 Inhibitor (CAS 191338-86-0), we are not able to provide the volume of water needed, but we recommend dissolving in deionized water at room temperature. Any unused solution can be stored at -20ºC or below. Long-term stability is undetermined, but to limit the number of freeze-thaw cycles the product is subjected to, we recommend sub-aliquoting your stock solution into smaller, single-used aliquots.
Answered by: Technical Support
Date published: 2017-01-31

Is this soluble in DMSO?

Asked by: chemicalsmg
Thank you for your question. This product is soluble in DMSO at 1 mg/ml. Please contact Technical Service if you have further questions concerning this product.
Answered by: Tech Service 9
Date published: 2016-12-28
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