caspase-1 substrate Inhibits the cleavage of the IL-1β precursor by ICE

caspase-1 substrate (CAS 143305-11-7)

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Synonym: IL-1B convertase substrate; NEAYVHDAPVRSLN
Application: Inhibits the cleavage of the IL-1β precursor by ICE
CAS Number: 143305-11-7
Purity: ≥93%
Molecular Weight: 1584.7
Molecular Formula: C68H105N21O23
* Refer to Certificate of Analysis for lot specific data (including water content).
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Caspase-1 substrate is an IL-1β convertase substrate. The Caspase-1 substrate sequence (NEAYVHDAPVRSLN) corresponds to the native cleavage site C-terminal to Asp-116 of the precursor IL-1β. Also functions as a competitive inhibitor of caspase-1.

Appearance :
Lyophilized powder
Physical State :
Solid
Sequence :
Asn-Glu-Ala-Tyr-Val-His-Asp-Ala-Pro-Val-Arg-Ser-Leu-Asn
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Certificate of Analysis

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