CASIN A Cdc42 GTPase inhibitor

CASIN (CAS 425399-05-9)

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Synonym: 2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol
Application: A Cdc42 GTPase inhibitor
CAS Number: 425399-05-9
Purity: ≥98%
Molecular Weight: 306.40
Molecular Formula: C20H22N2O
* Refer to Certificate of Analysis for lot specific data (including water content).
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CASIN is a Cdc42 GTPase inhibitor (IC50 = 2 μM). It reduces active levels of Cdc42 in aged hematopoietic stem cells (HSCs) to that in young HSCs and reverses the aging-related and polarity phenotype of aged HSCs to that of young HSCs. CASIN also increases histone H4K16 acetylation in aged HSCs.

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM), and ethanol (50 mM).
Storage :
Store at -20° C
Melting Point :
215.08 °C (Predicted)
Boiling Point :
~577.8 °C at 760 mmHg (Predicted)
Density :
~1.2 g/cm3 (Predicted)
Refractive Index :
n20D 1.68 (Predicted)
IC50 :
Cdc42 GTPase: IC50 = 2 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
2882155
SMILES :
C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)C4=CC=CC=C4)NCCO

Download SDS (MSDS)

Certificate of Analysis

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