Carnosol is a naturally occurring phytopolyphenol found in rosemary that functions as an antioxidant, antimicrobial, and anticarcinogen. Carnosol has been shown to inhibit inductions of COX-2 by blocking PKC signaling. Carnosol is an inhibitor of AR and ER α.
Subbaramaiah K, Cole PA, Dannenberg AJ. Cancer Res. 62:2522-30 (2002). Lo AH, Liang YC, Lin-Shiau SY et al. Carcinogenesis. 23:983-91 (2002).
Soluble in DMSO (250 mg/ml), ethanol (8 mg/ml), methanol (5 mg/ml), DMF (35 mg/ml), and PBS(pH7.2) (<0.03 mg/ml).
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