Carbenicillin disodium salt A β-lactam antibiotic

Carbenicillin disodium salt (CAS 4800-94-6)

Carbenicillin disodium salt | CAS 4800-94-6 is rated 5.0 out of 5 by 1.
  • y_2019, m_2, d_22, h_16
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.11
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202519, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 307ms
  • REVIEWS, PRODUCT
Synonym: α-Carboxybenzylpenicillin disodium salt
Application: A β-lactam antibiotic
CAS Number: 4800-94-6
Purity: ≥90%
Molecular Weight: 422.36
Molecular Formula: C17H16N2O6S•2Na
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Carbenicillin disodium salt is a penicillin-derived, β-lactam antibiotic which inhibits the synthesis of peptidoglycan, a key component of the bacterial cell wall. In studies investigating the roles of biogenic polyamines, spermidine and spermine, on antibiotic susceptibility of several microorganisms it was observed that the mean inhibitory concentration (MIC) of β-lactam antibiotics such as Carbenicillin was decreased with the addition of spermidine and spermine to cultures of Escherichia coli and Salmonella enterica. Additionally, in plants Carbenicillin was investigated for its effects on morphology and growth of Beta vulgaris, Capsicum annuum and Glehnia littoralis roots. In this study, Carbenicillin was noted to inhibit root elongation while promoting root branching in contrast to Ampicillin (sc-202951).


References

1. Itoh, T., et al. 1993. Antimicrob. Agents Chemother. 37: 2327-2332. PMID: 8285614
2. Lloyd, J.R., et al. 1997. Appl. Microbiol. Biotechnol. 48: 155-161. PMID: 9299772
3. Melano, R., et al. 2002. Antimicrob. Agents Chemother. 46: 2162-2168. PMID: 12069969
4. ur Rahman, L., et al. 2004. Plant Cell Rep. 22: 668-677. PMID: 14727052
5. Samuilov, V.D., et al. 2008. Biochemistry Mosc. 73: 833-838. PMID: 18707592
6. Goytia, M. and Shafer, W.M. 2010. Infect. Immun. 78: 3187-3195. PMID: 20439477

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (50 mg/ml), and alcohol.
Storage :
Store at -20° C
Melting Point :
>200° C
Refractive Index :
n20D ~1.68
Ki Data :
Solute carrier family 22 member 6: Ki= 1.28 mM (mouse); Solute carrier family 22 member 20: Ki= 1.33 mM (mouse)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
RTECS :
ON9105000
PubChem CID :
20933
Merck Index :
14: 1792
MDL Number :
MFCD00077683
EC Number :
225-360-8
Beilstein Registry :
5722128
SMILES :
CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)C(=O)[O-])C(=O)[O-])C.[Na+].[Na+]

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Carbenicillin disodium salt  Product Citations

See how others have used Carbenicillin disodium salt. Click on the entry to view the PubMed entry .

Citations 1 to 4 of 4 total

Neskorodov, Ya B. et al. 2010. Plant Cell, Tissue and Organ Culture. 100: 65-71.

Zhangsun, D et al. 2007. Biologia. 62: 386-393.

PMID: # 17314094  Yonekura-Sakakibara, K. et al. 2007. J. Biol. Chem. 282: 14932-14941.

PMID: # 8071330  Katayama, T. et al. 1994. J. Biol. Chem. 269: 22075-22079.

Citations 1 to 4 of 4 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 71ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Various publications cite the use of Carbenicillin Various publications cite the use of Carbenicillin disodium salt in the preparation of selective media. -SCBT Publication Review
Date published: 2015-04-29
  • y_2019, m_2, d_22, h_16
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.11
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202519, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 37ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.