Bromobimane A fluorescent thiol probe

Bromobimane (CAS 71418-44-5)

Bromobimane | CAS 71418-44-5 is rated 5.0 out of 5 by 1.
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Synonym: Monobromobimane; MBBR
Application: A fluorescent thiol probe
CAS Number: 71418-44-5
Molecular Weight: 271.11
Molecular Formula: C10H11BrN2O2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Bromobimane is a fluorescent probe that readily reacts with low molecular weight and protein thiols. It is almost non-fluorescent until it is conjugated to thiol. The reagent is particularly useful for quantifying glutathione.


References

Kosower, N.S., et al. Proc. Natl. Acad. Sci. USA 76, 3382, (1979); Danielsohn, P. and Nolte, A. Histochemistry 86, 281, (1987)

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (partly), DMSO, DMF, methanol (25 mg/ml), and chloroform.
Storage :
Store at -20° C
Melting Point :
161° C
Boiling Point :
~327.8° C at 760 mmHg (Predicted)
Density :
~1.7 g/cm3 (Predicted)
Refractive Index :
n20D 1.64 (Predicted)
Fluoresence :
λex 384 nm, λem 462 nm in methanol; λex 390 nm, λem 478 nm in 0.1 M phosphate pH 7.5 (after derivatization with glutathione); λex 398 nm
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
114810
MDL Number :
MFCD00036951
Beilstein Registry :
4430959
SMILES :
CC1=C(N2C(=C(C(=O)N2C1=O)C)CBr)C

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Ju et al Ju et al. (PubMed ID 19394283) used Bromobimane to visualize 2,3-dimercaptosuccinic acid in mice blood and tissues via HPLC using fluorescence. -SCBT Publication Review
Date published: 2015-02-05
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