Brij 35 For isolation of functional cell membrane complexes

Brij 35 (CAS 9002-92-0)

Brij 35 | CAS 9002-92-0 is rated 5.0 out of 5 by 1.
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Synonym: Polyoxyethyleneglycol Dodecyl Ether
Application: For isolation of functional cell membrane complexes
CAS Number: 9002-92-0
Molecular Formula: (C2H4O)nC12H26O
* Refer to Certificate of Analysis for lot specific data (including water content).
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Brij 35® is a polyglycol ether which functions as a detergent for the isolation of functional cell membrane complexes. Studies indicate that Brij 35® acts as a surfactant in Micellar electrokinetic chromatography (MEKC). It is known that Brij 35® is also beneficial in UV monitoring of solubilized proteins due to their low UV absorbance. This compound is useful in slowing down electroosmotic pumping, which allows users to change pH values without drastically altering the flow rate.


References

1. Ashani, Y. and Catravas, G.N. 1980. Anal. Biochem. 109: 55-62. PMID: 7469018
2. Arnaud, N. and Georges, J. 2001. Spectrochim Acta A Mol Biomol Spectrosc. 57A: 1085-1092. PMID: 11374568
3. Rukhadze, M., et al. 2011. Biomed Chromatogr. PMID: 21381065

Physical State :
Solid
Solubility :
Soluble in water (40 mg/ml) at 20 °C, methanol, and ethanol.
Storage :
Store at room temperature
Melting Point :
41-45° C (lit.)
Boiling Point :
100° C
Density :
1.06 g/cm3 (Predicted)
Refractive Index :
n20D 1.47 (Predicted)
IC50 :
Human immunodeficiency virus 1: IC50 = 47000 nM (Human immunodeficiency virus 1)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
JR5990000
PubChem CID :
2724258
Merck Index :
14: 7558
MDL Number :
MFCD00080891
EC Number :
500-002-6
SMILES :
CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

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Certificate of Analysis

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Brij 35  Product Citations

See how others have used Brij 35. Click on the entry to view the PubMed entry .

Citations 1 to 6 of 6 total

PMID: # 26642846  Wang, H. et al. 2016. Molecular reproduction and development. 83: 132-43.

PMID: # 26485177  Tran, TB. et al. 2016. Biosensors & bioelectronics. 77: 631-7.

PMID: # 26870238  Xiong, W. et al. 2016. Oncol Lett. 11: 484-490.

PMID: # 26725932  Nguyen, PD. et al. 2015. Biosensors & bioelectronics.

PMID: # 25954874  Nguyen, TA. et al. 2015. Biophysical journal. 108: 2158-70.

PMID: # 23843240  Li, YH. et al. 2013. Biology of reproduction. 89: 53.

Citations 1 to 6 of 6 total
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Rated 5 out of 5 by from Numerous publications cite the use of this Numerous publications cite the use of this detergent (Brij 35) in various applications involving protein interactions/extractions. -SCBT Publication Review
Date published: 2015-03-03
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