Boc-L-aspartic acid beta-benzyl ester chloromethylketone An Apoptosis inhibitor

Boc-L-aspartic acid beta-benzyl ester chloromethylketone (CAS 172702-58-8)

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Synonym: Boc-Asp(OBzl)-CMK
Application: An Apoptosis inhibitor
CAS Number: 172702-58-8
Purity: ≥95%
Molecular Weight: 355.81
Molecular Formula: C17H22NO5Cl
* Refer to Certificate of Analysis for lot specific data (including water content).
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Boc-L-aspartic acid beta-benzyl ester chloromethylketone is cell penetrable. This inhibitor has been shown to bind covalently to the active site of ICE, reducing ICE-mediated processing of mature interleukin-1β in a monocytic cell line without affecting tumor necrosis factor processing.


References

1. Boudreau, N., et al., 1995. Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science (New York, N.Y.). 267(5199): 891-3. PMID: 7531366

Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
7020821
SMILES :
CC(C)(C)OC(=O)N[C@@H](CC(=O)OCC1=CC=CC=C1)C(=O)CCl

Download SDS (MSDS)

Certificate of Analysis

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