BIS-Tris An inert, zwitterionic buffer that exhibits only a very small shift in dissociation constant

BIS-Tris (CAS 6976-37-0)

BIS-Tris | CAS 6976-37-0 is rated 5.0 out of 5 by 1.
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Synonym: Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane
Application: An inert, zwitterionic buffer that exhibits only a very small shift in dissociation constant
CAS Number: 6976-37-0
Purity: ≥98%
Molecular Weight: 209.24
Molecular Formula: C8H19O5N
* Refer to Certificate of Analysis for lot specific data (including water content).
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BIS-Tris is an inert, zwitterionic buffer that exhibits only a very small shift in dissociation constant with respect to temperature. Suitable for fractionation of hemoglobin. The useful pH range for the buffer is 5.8-7.2. Has a pKa of 6.5 at 25°C.


References

Nealon, D.A., et al. 1980. Clin Chem. 26, 1516. Morin, L.G. 1977. Clin. Chem. 23, 1569.

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (~209.2 g/l) at 20° C, and alcohol.
Storage :
Store at room temperature
Melting Point :
102-105° C
Boiling Point :
~466.18° C at 760 mmHg (Predicted)
Density :
~1.3 g/cm3 (Predicted)
Refractive Index :
n20D 1.56 (Predicted)
pK Values :
pKa: 6.5 at 25° C (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
81462
MDL Number :
MFCD00002853
EC Number :
230-237-7
Beilstein Registry :
2205275
SMILES :
C(CO)N(CCO)C(CO)(CO)CO

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Certificate of Analysis

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BIS-Tris  Product Citations

See how others have used BIS-Tris. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 24138583  Cockrell, GM. et al. 2013. Biochemistry. 52: 8036-47.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Various publications cite BIS Various publications cite BIS-Tris as an inert, zwitterionic buffer that exhibits only a very small shift in dissociation constant with respect to temperature. Suitable for fractionation of hemoglobin. -SCBT Publication Review
Date published: 2015-05-08
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