BIMU 8A potent full agonist of SR-4

BIMU 8 (CAS 134296-40-5)

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Application: A potent full agonist of SR-4
CAS Number: 134296-40-5
Molecular Weight: 378.9
Molecular Formula: C19H26N4O2.HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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BIMU 8 is a potent SR-4 full agonist with a KD of 77 nM and EC50 = 18 nM for wild type SR-4. BIMU 8 binds to receptors in a mechanism different to that of the endogenous ligand 5-HT.

Physical State :
Solid
Solubility :
Soluble in water (75 mM), DMSO (100 mM), and ethanol (100 mM).
Storage :
Store at 4° C
IC50 :
wild type 5-HT4 receptors: EC5050 = 18 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5311028
MDL Number :
MFCD00903899
SMILES :
CC(C)N1C2=CC=CC=C2N(C1=O)C(=O)NC3C[C@H]4CC[C@@H](C3)N4C.Cl

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Certificate of Analysis

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BIMU 8  Product Citations

See how others have used BIMU 8. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 28082431  Mondal, A. et al. 2017. Physiol Rep. 5:

Citations 1 to 1 of 1 total
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