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Bilirubin is a principal pigment of bile and one of the major end products of hemoglobin decomposition. It contains conjugated double bonds and reactive hydrogen atoms. Serves as a physiological antioxidant. Reported to cross the blood-brain barrier and exert significant antioxidant effects in the brain. This product corresponds to the unconjugated form. Extinction coefficient (454 nm, CHCl3):59,100-62,300 M-1cm-1.
1. Scigliano, G., et al. 1997. Ital. J. Neurol. Sci. 18: 69-72. PMID: 9239525
2. Ossola, J.O., et al. 1998. Int. J. Biochem. Cell Biol. 30: 285-292. PMID: 9608682
See how others have used Bilirubin. Click on the entry to view the PubMed entry .
PMID: # 25638774
Abdalla, MY. et al. 2015. Induction of heme oxygenase-1 contributes to survival of Mycobacterium abscessus in human macrophages-like THP-1 cells. Redox Biol. 4: 328-39.
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