Bicyclomycin A streptomyces metabolite with selective Gram negative profile

Bicyclomycin (CAS 38129-37-2)

Bicyclomycin | CAS 38129-37-2 is rated 5.0 out of 5 by 1.
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Synonym: Bicozamycin; Aizumycin; Bacteron
Application: A streptomyces metabolite with selective Gram negative profile
CAS Number: 38129-37-2
Purity: ≥95%
Molecular Weight: 302.28
Molecular Formula: C12H18N2O7
* Refer to Certificate of Analysis for lot specific data (including water content).
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Bicyclomycin is a polar metabolite first isolated from Streptomyces sapporonensis in 1972. The selective Gram negative profile of bicyclomycin is rare among Streptomyces metabolites. The primary site of action for bicyclomycin is thought to be the rho transcription termination factor.

Physical State :
Solid
Derived From :
Streptomyces sp.
Solubility :
Soluble in ethanol, methanol, DMF, DMSO, and water.
Storage :
Store at -20° C
Melting Point :
255.06° C (Predicted)
Boiling Point :
~786.6° C at 760 mmHg (Predicted)
Density :
~1.6 g/cm3 (Predicted)
Refractive Index :
n20D 1.63 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
65807
MDL Number :
MFCD00865145
EC Number :
253-795-3
SMILES :
C[C@](CO)([C@@H]([C@@]12C(=O)N[C@@](C(=C)CCO1)(C(=O)N2)O)O)O

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Bicyclomycin  Product Citations

See how others have used Bicyclomycin. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25999346  D'Heygère, F. et al. 2015. Nucleic Acids Res. 43: 6099-111.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Magyar Magyar, A. et al. (PubMed 8810302) reported that the antibiotic Bicyclomycin affects the secondary RNA binding site of Escherichia coli transcription termination factor Rho. -SCBT Publication Review
Date published: 2015-03-26
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