BI-6C9 A tBid inhibitor that possesses antiapoptotic properties

BI-6C9 (CAS 791835-21-7)

BI-6C9 | CAS 791835-21-7 is rated 5.0 out of 5 by 1.
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Synonym: N-[4-[(4-Aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-Butanamide
Application: A tBid inhibitor that possesses antiapoptotic properties
CAS Number: 791835-21-7
Purity: ≥97% (HPLC)
Molecular Weight: 471.59
Molecular Formula: C23H25N3O4S2
* Refer to Certificate of Analysis for lot specific data (including water content).
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BI-6C9 ( N-[4-[(4-Aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-Butanamide) is a tBid inhibitor that possesses antiapoptotic properties.


References

1. Wei, M.C., et al. 2000. Genes Dev. 14: 2060-2071. PMID: 10950869
2. Becattini, B. 2004. Chem. Biol. 11: 1107-1117. PMID: 15324812

Physical State :
Solid
Solubility :
Soluble in DMSO: 24 mg/mL
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
11547341
SMILES :
COC1=CC=C(C=C1)S(=O)(=O)NCCCC(=O)NC2=CC=C(C=C2)SC3=CC=C(C=C3)N

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BI-6C9  Product Citations

See how others have used BI-6C9. Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 25301069  Skliris, A. et al. 2015. Cell Death Differ. 22: 703-18.

PMID: # 24688051  Kuzu, O.F. et al. 2014. Molecular cancer therapeutics. 13: 1690-703.

Citations 1 to 2 of 2 total

why no one using this inhibitor for in vivo studies

Asked by: pree
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Rated 5 out of 5 by from Zhou H; et al Zhou H; et al. (PubMed ID: 24628719) determined that BI-6C9 prevented cell death in matrine exposed HepG2 cells. -SCBT Publication Review
Date published: 2015-01-22
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