BAPTA, Free Acid (1,2-bis-(o-Aminophenoxy)-ethane-N,N,N′,N′-tetraacetic acid) is a selective calcium chelator with 105-fold greater affinity for Ca2+ than for Mg2+. This product is a high quality and sensitive compound for calcium signaling studies, investigation of signal transduction and apoptotic cascades, and neuroscience research. BAPTA, Free acid is not cell permeable and is useful for manipulating extracellular Ca2+ levels. BAPTA is closely related to the well-known chelator EGTA [ethylene glycol bis(beta-aminoethyl ether)-N,N,N′,N′-tetraacetic acid] (sc-3593), but is less effected by pH changes and are more efficient at taking up and releasing Ca2+.
Additional BAPTA chelators available:
BAPTA tetrapotassium salt (sc-202076)
5,5i difluoro Bapta(AM) (sc-217247)
5,5i difluoro Bapta(K+ Salt) (sc-217248)
Bapta-FF (AM) (sc-217696)
BAPTA, Tetrasodium Salt (sc-278716)
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See how others have used BAPTA, Free Acid. Click on the entry to view the PubMed entry .
PMID: # 28497254 Angstadt, JD. et al. 2017. J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol. 203: 613-633.
PMID: # 27865353 Mohan, S. et al. 2016. Nutrition research (New York, N.Y.). 36: 1114-1120.
PMID: # 26673139 Galindo-Villegas, J. et al. 2016. J. Immunol. 196: 738-49.
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