BAPTA-APM A fluorescent Ca2+ chelator used to study the physiological role of cytosolic free calcium

BAPTA-APM (CAS 352000-08-9)

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Application: A fluorescent Ca2+ chelator used to study the physiological role of cytosolic free calcium
CAS Number: 352000-08-9
Molecular Weight: 699.92
Molecular Formula: C26H29K4N3O10
* Refer to Certificate of Analysis for lot specific data (including water content).
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BAPTA-APM [5-(3-Aminopropyl)-5'-methyl-bis-(2-aminophenoxy-methylene)-N,N,N',N'-tetraacetate, tetrapotassium salt] is a fluorescent chelating indicator used to study cytosolic free calcium. Fluorescent calcium indicators selectively bind to calcium ions and show a spectral response upon binding Ca2+; thus, fluorescence intensity or wavelength are altered. This shift of fluorescence wavelength and change of intensity upon calcium chelation can be monitored using fluorescence microscopy. This high quality fluorescent Ca2+ chelator is useful for many intracellular applications, especially in single cells, adherent cell layers, or bulk tissues.
Additional BAPTA chelators available:
BAPTA, Free Acid (sc-201508)
BAPTA tetrapotassium salt (sc-202076)
BAPTA/AM (sc-202488)
BAPTA-TMFM (sc-212043)
5,5i difluoro Bapta(AM) (sc-217247)
5,5i difluoro Bapta(K+ Salt) (sc-217248)
Bapta-FF (AM) (sc-217696)
BAPTA, Tetrasodium Salt (sc-278716)


References

1. Cannon, C., et al. 1985. Nature. 314: 443-446. PMID: 2858819

Physical State :
Solid
Solubility :
Soluble in water, ethanol, and methanol.
Storage :
Store at -20° C
Melting Point :
255-260° C (dec.)
Boiling Point :
841.3° C at 760 mmHg (Predicted)
Refractive Index :
n20D ~1.64 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
3565208
MDL Number :
MFCD08445442
SMILES :
CC1=CC(OCCOC2=C(C=CC(CCCN)=C2)N(CC(=O)O[K])CC(=O)O[K])=C(C=C1)N(CC(=O)O[K])CC(=O)O[K]

Download SDS (MSDS)

Certificate of Analysis

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