Aristoforin A highly-stable SIRT inhibitor used for research purposes

Aristoforin (CAS 849215-53-8)

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Synonym: SIRT inhibitor
Application: A highly-stable SIRT inhibitor used for research purposes
CAS Number: 849215-53-8
Purity: ≥95%
Molecular Weight: 594.83
Molecular Formula: C37H54O6
* Refer to Certificate of Analysis for lot specific data (including water content).
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Aristoforin is a stable and water-soluble derivative of hyperforin inducing apoptosis. Antitumor agent. Aristoforin also inhibits SIRTs. SIRTs are known to deacetylate histones.


References

1. Gartner, Michael., et al., 2005. Aristoforin, a novel stable derivative of hyperforin, is a potent anticancer agent. Chembiochem : a European journal of chemical biology. 6(1): 171-7. PMID: 15593112
2. Gey, Claudia., et al., 2007. Phloroglucinol derivatives guttiferone G, aristoforin, and hyperforin: inhibitors of human sirtuins SIRT1 and SIRT2. Angewandte Chemie (International ed. in English). 46(27): 5219-22. PMID: 17516596

Appearance :
Oil
Physical State :
Liquid
Solubility :
Soluble in DMSO or 100mM sodium hydrogen carbonate/2% DMSO.
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Download SDS (MSDS)

Certificate of Analysis

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