apo-Transferrin Biologically active protein: a non-heme iron transport protein

apo-Transferrin (CAS 11096-37-0)

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Synonym: ATF; Siderophilin; Serotransferrin; β-1-metal-binding globulin
Application: A non-heme iron transport protein
CAS Number: 11096-37-0
Molecular Weight: 76-81 kDa
* Refer to Certificate of Analysis for lot specific data (including water content).
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Apo-Transferrin (ATF) is sourced from FDA approved plasma and has been tested and found negative for antibodies to many common human blood viruses. ATF plays a physiological role in the transportation and distribution of iron amongst bodily organs. Apo-Transferrin is also an important component used for the cultivation of mammalian cells in-vitro because it acts as a transport factor for defined culture media. This property is crucial for long-term mammalian cell growth in-vitro since ATF operates as a detoxificant in media by binding to contaminating metal ions. Some other common uses for Apo-Transferrin are affinity purification and receptor mediated transfection of DNA-like molecules into cells.

Physical State :
Solid
Derived From :
human
Solubility :
Soluble in water (50 mg/mL).
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
MDL Number :
MFCD00130536
EC Number :
234-318-8

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Certificate of Analysis

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How can I bind in vitro Fe(III) to apo-transferrin?

Asked by: Anca
Thank you for your question. We do not have a protocol for use of this product, but per the CoA this has an iron binding capacity of 1.2 - 1.6 μg/mg.
Answered by: Technical Support
Date published: 2017-09-25
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