Anpirtoline hydrochloride is a selective agonist of SR-1B. Anpirtoline shows strong selectivity at SR-1B (Ki = 28 nM) over the SR-1A (Ki = 150 nM) and SR-2 (Ki = 1.49 μM) serotonin receptor subtypes. Anpirtoline is also described to produce antagonism at the SR-3 (Ki = 29.5 nM).
1. Schlicker, E., et al. 1992. Br. J. Pharmacol. 105: 732-738. PMID: 1628159 2. Swedberg, M.D., et al. 1992. J. Pharmacol. Exp. Ther. 263: 1015-1022. PMID: 1335050 3. Göthert, M., et al. 1995. Br. J. Pharmacol. 114: 269-274. PMID: 7881726 4. de Almeida, R.M., et al. 2002. Neuropsychopharmacology. 27: 171-181. PMID: 12093591 5. Watanabe, A., et al. 2006. Nucl. Med. Biol. 33: 325-332. PMID: 16631081
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