AMTB hydrochlorideAn inhibitor of TRPM8 channel

AMTB hydrochloride (CAS 926023-82-7)

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Synonym: N-(3-Aminopropyl)-2-[(3-methylpheny l)methoxy]-N-(2-thienylmethyl)benzamide hydrochloride
Application: An inhibitor of TRPM8 channel
CAS Number: 926023-82-7
Molecular Weight: 430.99
Molecular Formula: C23H26N2O2S•HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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AMTB is a TRPM8-selective antagonist with no cross reactivity to TRPV1 or 4. The pIC50 of icilin activation of TRPM8 is 6.23.


References

1. Lashinger , E.S., et al. 2008. Am. J. Physiol. Renal Physiol. 295: 803-810. PMID: 18562636

Physical State :
Solid
Solubility :
Soluble in water (100 mM), and DMSO (100 mM).
Storage :
Desiccate at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
16095383
MDL Number :
MFCD18086917
SMILES :
CC1=CC(=CC=C1)COC2=CC=CC=C2C(=O)N(CCCN)CC3=CC=CS3.Cl

Download SDS (MSDS)

Certificate of Analysis

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