AMPK Activator AMPK Activator is a furancarboxylic acid derivative that can permeate the cell and partially inhibit the mitochondrial complex I.

AMPK Activator  (CAS 849727-81-7)

AMPK Activator is rated 5.0 out of 5 by 1.
  • 2016-09-25T11:57CST
  • bvseo_cps, prod_bvrr, vn_cps_3.4.0
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_203819, PRD, sort_relevancy
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 76ms
  • REVIEWS, PRODUCT
Synonym: 5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid, D942
Application: A cell-permeable AMP-activated protein kinase (AMPK) activator and survivin inhibitor
CAS Number: 849727-81-7
Purity: >95%
Molecular Weight: 368.40
Molecular Formula: C22H21FO4
* Refer to Certificate of Analysis for lot specific data (including water content).
submit a review for this product and receive 15 cruzcredits

Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
AMPK sc-203819 5 mg $225.00

AMPK Activator is a furancarboxylic acid derivative that can permeate the cell and partially inhibit the mitochondrial complex I. Research shows that AMPK Activator increases glucose uptake in L6 myocytes, and inhibits CCL2-induced mTORC1 activity and survivin expression in human prostate cancer PC-3 cells (sc-2220). In multiple myeloma cells, AMPK Activator inhibits cell growth.


References

1. Kosaka, T., et al. 2005. Anal. Chem. 77: 2050-2055. PMID: 1580173
2. Baumann, P., et al. 2007. Exp. Cell Res. 313: 3592-3603. PMID: 17669398
3. Roca, H., et al. 2009. Neoplasia. 11: 1309-1317. PMID: 20019839

Physical State :
Solid
Solubility :
DMSO, methanol
Storage :
Store at 4° C
Melting Point :
134° C
Boiling Point :
~538.48° C at 760 mmHg (Predicted)
Density :
~1.23 g/cm3 (Predicted)
Refractive Index :
n20D 1.58 (Predicted)
IC50 :
glucose uptake: EC5050 = 11.7 µM (L6 myocytes)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
16760291
SMILES :
C1=CC(=CC=C1CCCC2=CC=C(O2)C(=O)O)OCCC3=CC=C(C=C3)F

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

You May Also Like

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 71ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from An increase in MAP LC3 protein expression in PC An increase in MAP LC3 protein expression in PC-3 cells was observed by WB when comparing untreated and AMPK Activator treated cells. -SCBT QC
Date published: 2015-02-07
  • 2016-09-25T11:57CST
  • bvseo_cps, prod_bvrr, vn_cps_3.4.0
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_203819, PRD, sort_relevancy
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 84ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2016 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.