Amantadine hydrochloride An NMDA-receptor antagoinst

Amantadine hydrochloride (CAS 665-66-7)

Amantadine hydrochloride | CAS 665-66-7 is rated 5.0 out of 5 by 1.
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Synonym: Symmetrel; Virofral; 1-​Adamantamine Hydrochloride
Application: An NMDA-receptor antagoinst
CAS Number: 665-66-7
Purity: ≥99%
Molecular Weight: 187.71
Molecular Formula: C10H17N•HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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Amantadine Hydrochloride is an NMDA-receptor antagonist and an antiviral agent.


References

Vernier, V.G., et al Toxicol. Appl. Pharmacol., 15, 642 (1969) Kirschbaum, J., et al.: Anal. Profiles Drug Subs., 12, 1 (1983)

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (50 mg/ml), ethanol (38 mg/ml at 25° C), chloroform (1:18), DMSO (38 mg/ml at 25° C), and methanol.
Storage :
Store at 4° C
Melting Point :
>300° C (lit.)
Refractive Index :
n20D 1.56 (Predicted)
IC50 :
Influenza A virus: EC5050 <900 nM; H2N2 subtype: EC5050 = 1.1 µM; Plasmodium falciparum: IC50 = 10 µM; Trypanosoma brucei: IC50 >132.4 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
AU4375000
PubChem CID :
64150
Merck Index :
14: 374
MDL Number :
MFCD00074723
EC Number :
211-560-2
Beilstein Registry :
4198854
SMILES :
C1C2CC3CC1CC(C2)(C3)N.Cl

Download SDS (MSDS)

Certificate of Analysis

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Amantadine hydrochloride  Product Citations

See how others have used Amantadine hydrochloride. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 27070720  Patel, K. et al. 2016. Molecular pharmaceutics. 13: 2049-58.

Citations 1 to 1 of 1 total

이 제품은 cell 실험에 사용할 수 있는 약제인가요?

Asked by: ys412
산타크루즈바이오테크놀러지에 문의 주셔서 감사합니다. 죄송합니다,cell 실험에 대한 정보는 제공하지 못합니다. 다른 문제 있으시면 기술지원팀에 연락하셔서 전화:86 21-60936350 이메일: asia@scbio.cn 또는 온라인문의로 문의하시면 됩니다. Thank you for your question.We are not able to find any relevant literature on this as an inhibitor in cell assay.If you have any other question ,please contact our Technical Service Department at email asia@scbio.cn,call us directly at (86 21) 6093-6350, or contact us by live chat.
Answered by: Technical Support 8
Date published: 2018-12-27
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Rated 5 out of 5 by from Chattopadhyaya Chattopadhyaya, I. et al. (PubMed 26306668) observed that Spirulina fusiform and Amantadine exhibited neuroprotective effects in the 6-OHDA induced Parkinsonism in rats. -SCBT Publication Review
Date published: 2015-05-23
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