Aluminum sulfate octadecahydrate has been used in a multitude of applications from a dyeing mordant to treating sewage. Aluminum has been implicated in either formation or stabilization of beta-pleated amyloid plaques which lead to pathologies such as Alzheimer's and Parkinson's disease; these beta sheet aggregates show similarity to amyloid plaques formed via the prion protein (mad cow disease). Aluminum sulfate octadecahydrate acts as a source of aluminium ions and can be used to probe the role of aluminium in these pathologies, and has shown ameliorative effects in models of fluorosis.
1. Kvech, S., et al. 2002. Water Res. 36: 4356-4368. PMID: 12420940 2. Kant, V., et al. 2010. Biol Trace Elem Res. 134: 188-194. PMID: 19652927 3. Anderson, M.A., et al. 2010. Chemosphere. [Epub ahead of print]. PMID: 20825969
Crystalline powder or chunks
Soluble in water (869 mg/ml at 0° C). Insoluble in alcohol.
Store at room temperature
1.69 g/cm3 at 16° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Various publications cite the use of AluminumVarious publications cite the use of Aluminum sulfate octadecahydrate as a source of aluminum ions used to probe aluminum's role in neural pathologies. -SCBT Publication Review
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