Alamethicin F50A potent antibiotic which forms voltage-dependent ion channels in lipid bilayers

Alamethicin F50 (CAS 56165-93-6)

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Synonym: Alamethicin F
Application: A potent antibiotic which forms voltage-dependent ion channels in lipid bilayers
CAS Number: 56165-93-6
Purity: >98%
Molecular Weight: 1963.32
Molecular Formula: C92H151N23O24
* Refer to Certificate of Analysis for lot specific data (including water content).
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Alamethicin F50 is a neutral linear peptaibol complex with potent antibiotic activity, containing 20 "amino acids" with an acetyl and phenylalaninol termini, produced by Trichoderma sp. Alamethicin F50 acts an ionopohore, transporting ions through membranes and artificial lipid membranes. Alamethicin F50 forms voltage- dependent ion channels in lipid bilayer membranes. Alamethicin F50 is co-produced with an acidic linear peptaibol complex (alamethicin F30). Alamethicin itself is a variable mixture of the acidic and neutral components. In general, reports on alamethicin do not specify the ratio of F50 to F30 in the complex and comparative data between the complexes is scant.

Physical State :
Solid
Derived From :
Trichoderma viride
Solubility :
Soluble in ethanol, methanol, DMSO, DMF, and water (poor).
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Certificate of Analysis

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